Metal?Catalyzed Reactivity Reversal in the Sulfonylation Reaction of ??Allenols: Controlled Synthesis of 4?(Arylsulfonyl)?2,5?Dihydrofurans

The synergy between metal catalysis and radical chemistry allows to surpass previous limitations of the reactions allenols sulfonylating reagents. Considering that studies reactivity allenol moiety with reagents have been limited addition rearrangement lacking cyclization, we decided modify protocol for achieving a catalytic cyclization/functionalization. In this way, accomplished copper-catalyzed cascade cycloetherification/sulfonylation controlled preparation 4-(arylsulfonyl)-2,5-dihydrofurans from sulfinates involving in situ-generated sulfur-centered radicals. generality our strategy was illustrated using various methyl- phenyl-substituted allenes.